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Potential therapeutic applications The therapeutic potential of glutathione in treating cold sores and canker sores can be harnessed through various approaches: Topical formulations: Developing creams or gels containing glutathione for direct application to cold sores and canker sores could provide localized antioxidative and anti-inflammatory effects

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The antitumor effect of ionizing radiation may be enhanced by triggering ferroptosis and ferroptosis inducers with effective radiosensitizers [71, 220,221,222,223,224]

Thirty five of the included studies were randomised controlled trialshowever, only 28 of these studies had a control group during both intervention and follow-up and were included in the analysis of randomised controlled trials