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Description

Damage-associated molecular patterns (DAMPs) released from pyroptotic cells further promote neutrophil activation and NETosis, contributing to sustained inflammation ( The dual roles of NETosis NETosis represents a specialized form of neutrophil cell death triggered by cellular activation, in which neutrophils release web-like structures composed of DNA, histones, and antimicrobial proteins as a defense mechanism against infection

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Detailed mechanistic investigations show that the cleavage of the selenoethyl arm proceeds through an anionic mechanism with assistance of the cysteine thiol group

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