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Statistical analyses All data calculations and statistical analyses were performed using the R software ( version 4.2.2)

Disclosures: David Lee: Nothing to Disclose, Caroline Klindt-Morgan: Nothing to Disclose, Dominick Hellen: Nothing to Disclose, Ashley Bennett: Nothing to Disclose, Paul Dawson: Nothing to Disclose, Saul Karpen: Albireo/Ipsen: Consultant, Mirum: Consultant, HemoShear: Consultant, Intercept: Consultant 718 THE USC PSYCHOSOCIAL CHECKLIST: A TOOL TO REMOTELY SCREEN POTENTIAL LIVER TRANSPLANT (LT) CANDIDATES WITH ALCOHOL-ASSOCIATED LIVER DISEASE (ALD) PRIOR TO HOSPITAL TRANSFER Brooke Edwards 1 Samantha Ramirez 1 John Pappas 2 Jennifer Dodge 2 Hyosun Han 3 Jeffrey Kahn 2 Norah Terrault 3 Aaron Ahearn 2 Brian Lee 4 , 1 Keck Medical Center of USC, 2 Keck USC, 3 University of Southern California, 4 Keck School of Medicine Background: ALD is the #1 indication for LT, leading to a rise in inter-hospital transfer requests for LT evaluation

This FGF8 signaling cascade subsequently activates Wnt1 expression in the midbrain, which in turn upregulates the Engrailed-1/2 transcription factorsfirst detected at embryonic days 11.514 in micewhereupon their sustained expression becomes essential for the maintenance and survival of VTA DA neurons (Hegarty et al., 2013)

Li C, Jiang P, Wei S, Xu X, Wang J