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Hepatology 78 , 637648 (2023)

Persistent vomiting or diarrhoea can lead to dehydration, which in turn may affect kidney function

This is why timely intervention is crucial when conservative treatment fails

The inactivation of Exportin-mediated export of OXS2 and hence nuclear accumulation of OXS2, and the autoactivation of its own gene, are all caused by oxidative stress and followed by the activation of a stress-induced pathway (Robert and David, 2004)