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bEnd3-GGT/KD cells with stable GGT knockdown were established using GGT-shRNA-Lentivirus according to our previous study 49

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2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS ) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+ ), and enhances the activity of glutathione peroxidase GPX4 , thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation

A near-infrared-responsive indocyanine-genistein nanoformulation has also been shown to be an effective novel formulation in the combinatorial photo- and chemotherapy of glioblastoma [164]