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Description

Itaconate also dampens NLRP3 activity after prolonged LPS exposure, playing an important role in the resolution of inflammation [117], and suppression of itaconate can contribute to chronic inflammation

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At upper panel, western blot analysis of Id2 and -tubulin in 3T3 fibroblasts at 6, 24, and 72 h of culture is shown

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The lipid peroxidation sensor BODIPY-C11 was used to evaluate LPO generation by light microscopy (Fig

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