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Importantly, the BBB functions as the core of the neurovascular unit (NVU), whose integrity depends on the coordinated homeostasis of surrounding neurons, astrocytes, and the basal lamina

*Exceeds 100 units (1mL)

Cuproptosis in ischemic stroke In ischemic stroke, the survival of neuronal cells is complex, with copper playing a crucial role (Tuo et al., 2022)

PBS (untreated), PEG-CeNPs, lCPP-CeNPs (3.0 mg/mL), low-concentration cCPP-CeNPs (1.0 mg/mL), high-concentration cCPP-CeNPs (3.0 mg/mL), and pirenoxine sodium eye drops groups were used in the experiments