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(Up to 250 mcg a day has been well-tolerated in people with Hashimotos.) Some potential factors that may lead me to suspect an iodine deficiency include: eating a diet low in seafood, eating a vegan diet , having fibrocystic breasts (though this could be caused by magnesium deficiency ), or having low reverse T3 levels

B12 supplements come in multiple forms, one being an over the counter orally ingested pill

While it is broken down by a few different enzymes (HNMT, NAT1,2 & DAO), it is the DAO (ref) responsible for the breakdown of ingested histamine

Use these if provided, as they are optimized for that peptide type