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301 MIF may play a key role in the pathogenesis of airway inflammation

The peptide activates melanocortin-4 receptors in the hypothalamus and melanocortin-3 receptors in limbic circuits, triggering dopamine release and nitric oxide synthesis in arousal pathways

Further, whereas bioinformatics suggests that ALDH3A1 is related to glycolysis, we found that ALDH3A1 expression could upregulate the level of glucose uptake, lactate level, and NAD + /NADH ratio, while it could downregulate the level of -KG (Fig