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POLG mutations in Alpers syndrome

For instance, Hevin promotes excitatory synapse formation by bridging neurxin 1 and neuroligin 1, whereas SPARC antagonizes this effect, thereby refining synaptic connections

When similar clinical studies are performed in humans, we will all have some baseline level of nutrients in our bodies simply because of the food we eat

Selenium status, for instance, differs dramatically by geography: populations in low-selenium regions may benefit from targeted intake, whereas those in replete environments risk toxicity with supplementation (199)