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How do neurexins modulating synaptic plasticity relate upstream and downstream to existing antidepressant mechanisms

All of the studies used both in vivo and some form of in vitro methods of data collection in order to observe different treatment effects, allowing for biomechanical, functional (use of AFI index and load to failure), macroscopic and microscopic histological analysis

DUBs are enzymes that cleave ubiquitin from target proteins and other molecules by hydrolyzing the ester, peptide, or isopeptide bonds at the carboxyl terminus of ubiquitin, thus counteracting ubiquitination-driven protein degradation 19,22,23

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