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Uremia can have a significant influence on the nervous system, possibly leading to a condition called uremic encephalopathy

Koga M, Seritella AV, Sawa A, Sedlak TW

A.et al (2018)

23-25 Further, pregnant women risk toxic exposure to the developing fetus since the mobilization of stored lead from the mothers bones can leach into the bloodstream, and this is more likely the result of chronic rather than acute lead exposure in the mother