Important safety warnings seek urgent medical attention if you experience: Severe or persistent abdominal pain, which may radiate to the back this could indicate pancreatitis , a serious but rare risk associated with GLP-1based therapies as a class [16] [17] Right upper quadrant pain, fever, or jaundice these may suggest gallbladder disease , another class-associated risk Signs of dehydration (dizziness, reduced urine output, extreme thirst) resulting from severe vomiting or diarrhoea, which can affect kidney function Pregnancy and breastfeeding: Use of GLP-1based therapies and related investigational agents is not recommended during pregnancy or breastfeeding
Muthusamy, T., Cordes, T., Handzlik, M
While recognizing that other mechanisms of immune enhancement may occur, the purpose of this Perspective is to review clinical experiences, in vitro analyses and animal models relevant to understanding the potential risks of antibody-dependent mechanisms and their implications for the development of the vaccines and antibodies that will be essential to stop the COVID-19 pandemic
This multitiered defence system comprises an endogenous antioxidant enzyme system (e.g., SOD/CAT/GPx) and small-molecule free radical scavengers such as vitamin C/E and -carotene, which are supported by trace elements such as selenium and zinc, collectively maintaining redox homeostasis [18]
