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Metabolism Changes: The body uses more glucose for energy, produces more ROS, and struggles to make proteins like enzymes and hormones

"Ellen Robillard O'Hara," by Patricia Patton Lawhon 3

Athletes may use IV drips (containing electrolytes, B vitamins, magnesium, and amino acids) to more quickly restore homeostasis, reduce soreness, and enhance recovery

The resulting albumin-cagrilintide complex: Is too large (~70,000 Da total) for glomerular filtration Is partially shielded from proteolytic degradation by albumin's spatial occupancy Functions as a reversible depot, slowly releasing free cagrilintide as albumin binding equilibrium dynamics allow Only the unbound (free) fraction of cagrilintide is pharmacologically active -- it binds amylin and calcitonin receptors in the central nervous system and periphery -- while the albumin-bound fraction serves as a circulating reservoir