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239 In an uncontrolled trial that included 15 women with fibromyalgia, seven of whom had also been diagnosed with chronic fatigue syndrome, treatment with a synbiotic (probiotic/prebiotic combination) for 30 days decreased stress, anxiety, and depression, improved quality of life, and reduced IL-8 levels

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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis