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PZQ alone cannot capably reverse pathological sequelae of schistosomiasis [19], and new therapies against schistosomiasis should focus also on this problem in addition to anthelmintic performance

The mechanism is likely due to the reduction of cytotoxicity from oxidative stress, inhibition of apoptosis in epidermal keratinocytes, and the promotion of growth factor expression, suggesting that HCG could be an effective skin protectant during clinical radiotherapy