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However, in the kidney tissue, which expresses high levels of NRK1, the effects of NR and NRH are comparable 125,128

Back Lau, J, Bloch, K, Schffer, L, et al (24 Sept 2015) 'Discovery of the once-weekly glucagon-like peptide-1 (glp-1) analogue Semaglutide', Journal Medicinal Chemistry , 58/18