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Btz, bortezomib

60,61 These advancements aim to improve patient experience, compliance, and treatment outcomes

Conclusion: ALG-055009 is a potent and selective THR- agonist with favorable in vitro safety and ADME properties and repeat-dose toxicity profile in rats and dogs

The DCCT study demonstrated that intensive insulin therapy in T1D significantly reduced the risk of DPN by 64% and cardiovascular autonomic neuropathy by 45% compared with conventional treatment, with these benefits persisting for over 13 years after the trial ended [60]