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Abstract Intervertebral disc degeneration (IVDD) is the leading cause of chronic low back pain (LBP), driven by a pathological microenvironment marked by acidic pH, increased reactive oxygen species (ROS), and elevated matrix metalloproteinase (MMP) activity, which hinder tissue regeneration

Mitochondrial respiration in fission yeasts is also required for the provision of amino acids during fermentative propagation (Malecki et al., 2020)

There is evidence that viral infections (hepatitis C, HIV and influenza) are associated with an increased production of ROS and that could be involved in the pathogenesis [33,34]

The fabric of our disposable shoe cover is thick, non-woven, and the corner details are carefully processed