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Potential Research Applications: Sleep regulation and circadian rhythm studies Stress adaptation and cortisol modulation research Neuroprotection and oxidative stress models Endocrine system and hormone balance investigations For laboratory research only

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This is consistent with the rapid decline in renal function without urinary protein excretion recently reported in DKD [2, 29]

The variant was detected in trans to a pathogenic variant (this case) (PM3), it is very rare (not detected in population databases according to gnomAD [9]) (PM2), prediction algorithms for splicing (Alamut program package) were in favor of a functional effect (PP3)