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Most 503A compounding pharmacies (state-licensed, patient-specific Rx compounders) do not have and cannot easily obtain a biologics license

However, the proposed anti-inflammatory and bronchodilator properties of VIP [121] make it a therapeutic option worth exploring

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For example esters and carbamates, which are either hydrolyzed by the low lysosomal pH or enzymatically by esterases and cytochrome P450 (Patterson et al., 1999