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The reason for this is the resistance of peptides composed of D-amino acids to enzymatic degradation, i.e., when used as pharmaceuticals these peptides are effective for a longer time

This allows for assessment of sustained effects while preventing potential receptor desensitization

Given that hepsin / mice were reported to have elevated mRNA levels of mitochondrial Cpt1b , Cpt2 , and Cox7a1 in adipose tissues compared with wild-type mice, suggesting a regulatory role for hepsin in metabolism (Li et al

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