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CMS may move a drug or biological product from a grouped billing and payment code to a unique billing and payment code in instances where the drug is either approved through the pathway established under section 505(b)(2) of the FD&C Act (hereinafter section 505(b)(2) drug products) that CMS initially assigned to the same billing and payment code as its reference drug for a period of time, or the drug was previously a multiple source drug but is now a single source drug that was moved to its own billing and payment code

Upon encountering an antigen, immature DCs transform into mature DCs due to their robust antigen phagocytic capacities

This section briefly introduces the mechanisms of action of these different NAD types and highlights drugs successfully applied in clinical settings (Fig

We are also grateful to our colleagues and collaborators for their invaluable in-sights and support throughout this article