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Deposition of collagen IV and aggrecan in leptomeningeal arteries of hereditary brain haemorrhage with amyloidosis

Such neuronal changes, or lesions, are characterized by tangles of nerve fibers and the increased presence of -amyloid and hyperphosphorylated tau in the brain, which ultimately leads to a decline in nervous system function

And here's a pro-tip we share with all our research partners: when you take a vial out of the freezer or fridge, let it come to room temperature for at least 30-60 minutes before opening the cap