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The SA- -Gal HI cells were nearly homogeneous, displaying the characteristic flattened shape and enlarged cell size of senescent cells with nuclei marked by senescence-associated heterochromatin foci (SAHF), increased immunoreactivity and delocalization of CDK inhibitor proteins p16 Ink4A and p21 Cip1 , and a disordered cytoskeleton with cytoplasmic filamentous (F) actin and nuclear monomeric (G) actin (Figure 1c)

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The degree of PL quenching was proportional to the concentration of TNT

While the intracellular reduction of Cr(VI) to Cr(III), which mostly occurs in the stomach, is believed to be a cause of genotoxicity and carcinogenicity, extracellular reduction is considered to be a detoxifying mechanism