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Reported reactions include: Reactive thrombocytosis Hypersensitivity: rash, pruritus, anaphylaxis Headache, paraesthesia, tremor Cardiac arrhythmias secondary to hypokalaemia Nausea, vomiting, diarrhoea Fever, chills, hot flushes, dizziness, malaise Injection site reactions: pain, erythema, pruritus, induration, swelling Acneiform and bullous eruptions Chromaturia (red/orange urine) Overdose Treatment is unlikely to be required

TB-500 became prominent in the early 2000s in horse racing, with reports stating that it could build muscle, promote recovery, decrease inflammation, increase red blood cell count, and stop bleeding in the animals

And while personal stories can be very compelling, they can create a perception of effectiveness that may not be fully supported by clinical evidence

doi:10.1101/cshperspect.a009183 Acknowledgments This work was supported by the Chang Gung Memorial Hospital [Grants CMRPD1A0531, CMRPD1C0231, CMRPG391311, CMRPG3A1131] and the Ministry of Science and Technology, Taiwan [Grant NMRPD181001-3]