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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

It plays a central role in cellular bioenergetics, providing ATP through OXPHOS and supporting macromolecular biosynthesis, including nucleotides, lipids, heme, and iron-sulfur clusters [156]

Pregnant or breastfeeding women should avoid Livagen absent specific medical supervision, as effects on fetal development and infant exposure through breast milk have not been studied

The higher dose (50 mg/kg) of MB effectively restored liver function markers, antioxidant status, hindered apoptosis and regulated iron regulatory proteins (ferritin and NCOA4 that reflects ferritinophagy) to levels comparable with the control group