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Our findings revealed that the overexpression of SREBP1 resulted in a significant reduction in intracellular lipid peroxides and MDA levels, while concurrently increasing the intracellular GSH content, when compared to the group treated with formononetin alone (Figures 4DF)

Several fatty acid beta-oxidation genes were differentially expressed with aging in the mouse olfactory bulb, including ACADM, acyl-CoA dehydrogenase family member 11 (ACAD11), hydroxyacyl-CoA dehydrogenase (HADH), hydroxyacyl-CoA dehydrogenase trifunctional protein subunit alpha (HADHA), acyl-CoA synthetase medium chain family member 3 (ACSM3), and acyl-CoA synthetase medium chain family member 4 (ACSM4) ( + ]/[NADH]

Usage Cited in: Acta Pharm Sin B

Their absorption and effectiveness are also subjects of ongoing scientific debate