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The two serines are not conserved in sequence in either Gpa-GSS22 or the remainder of Clade 3 (inset), but the equivalent residues are preferentially small and uncharged amino acids that do not vary greatly in the remainder of Clade 3 (inset)

Nat Protoc 5 , 5166 (2010)

High prevalence of gout in patients with Type 2 diabetes: male sex, renal impairment, and diuretic use are major risk factors

When you dont get enough sleep, your risk of developing chronic issues, including hypertension, heart disease, diabetes, depression, and obesity, increases dramatically