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Description

PMID 10416260

Ghasemzadeh, M

The unbalanced regulation of the glutathione synthesis coupled with the rapid and steady increase of glutathione abundance in the wheat tissue of the infested resistant plants suggested that the -glutamylcysteine synthetase might be either inhibited by a negative feedback from GSH, or it is not the rate-limiting enzyme in the glutathione synthetic pathway in wheat plants under our experimental conditions

It was observed that the most well studied membrane bound GST, microsomal glutathione transferase 1 (MGST1, EC number: 2.5.1.18) shared similarities with leukotriene C4 synthase (LTC4S, EC number: 4.4.1.20), catalyzing the conjugation reaction between leukotriene (LT) A4 and GSH