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Although CS-PDMS films have been developed as laser ultrasound transducers 2325 , our study represents the first instance of engineering them into a sandwich-structure

In addition, drug development targeting the gut-brain axis is in the exploratory phase

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In particular, iTregs generated in the presence of TGFb and rapamycin led to a polyclonal product enriched in FOXP3 + CD25 + CD4 + T cells that was clinically evaluated, depicting a favourable profile encouraging the phase II component for efficacy assessment [38]