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5-HT) type 1 receptor agonists ("triptans")), drugs that impair the metabolism of serotonin (e.g., MAO inhibitors), or antipsychotics or other dopamine antagonists

Consequently, SCLC cells exhibit a reduced ROS-scavenging capacity and, unlike non-cancerous cells, are unable to adapt to drug-induced ROS stress via NRF2-mediated mechanisms