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Importantly, the interpretive framework proposed here considers the ASI primarily as a descriptor of the current functional state of the HPAimmune axis and its circadian coordination, rather than as a fixed trait measure

Similarly, if glycolysis and glycogen mobilization are impaired by application of 2DG, the ATP content is lowered within several hours only by around 50% as endogenous energy stores are used for mitochondrial ATP regeneration under such conditions [67]

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After inoculation, the nude mice were put back into the cage without any special discomfort