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The theory implies that there is a causal mechanism that biologically sensitizes drug users, making them more willing to tryand more desirous ofharder drugs. The most important words here are these: IMPLIES CAUSAL Lets take a look at the word CAUSAL first

EFFECT OF NICOTINE ON THE GASTROINTESTI-NAL SYSTEM Acknowledging how nicotine affects ulcer formation and repair in the GI mucosa through both physiological and pathological processes has advanced significantly over the past 20 years [9]

Not only does it provide a pleasant smoke with its sweet and mellow taste, but it also is a great value for money when compared to other brands of tobacco on the market

They are working with the Centers for Disease Control and Prevention (CDC) to investigate the cause of these illnesses