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There was no correlation between either baseline Hcy or MMA concentrations with the maximum elevation of plasma dUrd in treatment cycle 1

B 124, 78197829

Furthermore, in activated T cells, increased aerobic glycolysis and glucose uptake result in rapid downregulation of TXNIP, further promoting glucose uptake and metabolism 154

As these transcriptional alterations suggest a reduction in hepatic fibrosis in response to lowering oxalate via AGXT overexpression, we next evaluated hepatic fibrosis through histopathological and immunofluorescence analyses coupled with biochemical verification