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On one hand, excess unstable -globin chains bind with heme to form haemichromes that are deposited in the erythroblasts membrane

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The peptide binds reversibly to G-actin (globular actin monomers) throughout the body, accumulating in tissues undergoing active remodeling or repair

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doi: 10.3389/fneur.2018.01033 Received 26 August 2018 Accepted 16 November 2018 Published 10 January 2019 Volume 9 - 2018 Edited by Kenneth Joseph Friedman, Medical School, Rutgers, The State University of New Jersey, United States Reviewed by Dinesh Upadhya, Manipal Academy of Higher Education, India

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