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There is also a condition called pernicious anaemia where your immune system prevents the cells in your stomach and gut from absorbing B12 from your food

Acute alcohol intake has been shown to decrease HDAC9 mRNA expression, leading to increased acetylation of the Fas promoter histone and increased chromatin accessibility

More often than not, studies investigating the prevalence of these polymorphisms in the above population are of small sample sizes, and did not incorporate the polymorphisms of all the three genes simultaneously (15, 16)

It can be synthesized in the skin through sunlight exposure and is also found in foods like fatty fish and fortified dairy products