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doi: 10.1002/14651858.CD000099.pub4 104 LanK-CLinP-YChangY-CChenY-JTsaiY-RIsmaeil MohamedISet al

The fluorescent labeling of these cells demonstrated the presence of initial apoptosis, subsequent apoptosis, and additional necrosis indicators, and their increase with contact extension (Sharaf et al., 2024b)

Die vier Stufen knnen wie folgt definiert werden [4]: Stufe 1: Information und Beratung (Empfehlung 52) Stufe 2: Aktives Abfragen und Einordnen (Empfehlung 53) Stufe 3: Prfen ob, Dosisreduktion, Umstellung oder Absetzen mglich sind (Empfehlung 54) Stufe 4: Spezifische Therapien Die ersten drei Stufen sind aufgrund ihres allgemeingltigen Charakters prinzipiell fr jede pharmakologische Therapie anzuwenden