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Melatonin was found to be most effective in restoring the creatinine and glutathione (GSH) levels as compare to ginkgo biloba, -lipoic acid and amrinone

For example, it leads to reduced hippocampal volume and impaired neurogenesis

Additionally, rs3743853 of hydroxyacyl glutathione hydrolase, also known as GLO2 , was in several three- and four-SNP models and therefore may be a good candidate gene for future studies