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Description

While it gained approval for HIV-associated lipodystrophy, its mechanism of action offers benefits that extend well beyond that specific condition

J.AbumweisS

More recently, gene rearrangements have been reported that give rise to AR versions that lack a functional ligand-binding domain (so-called AR variants (ARvs), making them unresponsive to ADT and constitutively active even in the absence of androgens [36]