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As an additional example to that of the trefoil peptides noted above, the peptide EGF (epidermal growth factor) is produced in human milk to promote growth of the gastrointestinal tract in newborn infants, but the same peptide aggressively stimulates the growth of breast cancer cells in adults

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Moreover, retinoids, when bound to RAR/RXR receptors (RAR: Retinoic Acid Receptor and RXR: Retinoid X Receptor), trigger a series of chromatin structure modifications that can encourage cell differentiation and initiate lasting epigenetic alterations

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