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The aberrant activity of these enzymes is closely linked with the pathogenesis of a wide range of diseases, not only cancers but also metabolic, inflammatory, and neurological disorders, underscoring the therapeutic relevance of targeting these pathways

7.4 Therapeutic potential of microglial regeneration Furthermore, microglial regeneration as a therapeutic approach holds significant promise, with adult brain-resident nestin-positive progenitor cells capable of rapidly proliferating and differentiating into ramified microglia under CSF1R signaling

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