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This ensures cellular growth, inhibits excessive melanin production, and helps to prevent DNA damage caused by oxidative stress 177,178

Similarly, transfection with pcDNA3.1-GST CEAM7 -ATP6AP1L resulted in an mRNA level of 34 times that of the control, and affinity cell sorting promoted the expression level to 94 times that of the control

Structure study of Nar1 revealed that the four conserved Cys residues, which are in the C-terminal of Nar1 are responsible for binding ISCs

Within cells, CYPs are predominately membrane-bound on the ER or mitochondria, with the ability to move along the membrane surface as the catalytic domain remains on the cytosolic side but is anchored by the N-terminal transmembrane on the luminal side (rejber et al., 2018)