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These core mechanisms include the synthesis of short-chain fatty acids (SCFAs) and vitamins, the promotion of immune system maturation, and the competitive exclusion of pathogenic microorganisms [35, 36]

All the experiments performed with human specimens were reviewed and approved by the Committees for Ethical Review of the Fourth Hospital of Harbin Medical University (2022-SCILLSC-28)

Metabolites were extracted using a previously described method 58,59

Overall, these findings highlight oligosaccharide prebiotics as versatile and scalable biotechnological ingredients, emphasizing the need for standardized production methods, precise dosing, and long-term clinical validation