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Substance use disorder began before the onset of panic, and substances were used to self-medicate for panic attacks by only a few subjects

For example: Government-sponsored researchers analyzing data from the Population Assessment of Tobacco and Health (PATH) Study found that adult smokers who used flavored e-vapor products were more than twice as likely to quit cigarette smoking than those who used non-flavored e-vapor products

Sobczak AJ (2003) The effects of tobacco smoke on the homocysteine levela risk factor of atherosclerosis

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