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BPC-157 and TB-500 are often co-studied because their published mechanisms operate on complementary axes of tissue repair BPC-157 on angiogenic, nitric-oxide and growth-factor pathways

Rev Med Virol 25:224240 Nasiri K, Mohammadzadehsaliani S, Kheradjoo H, Shabestari AM, Eshaghizadeh P, Pakmehr A, Alsaffar MF, Al-Naqeeb BZT, Yasamineh S, Gholizadeh O (2023) Spotlight on the impact of viral infections on Hematopoietic Stem Cells (HSCs) with a focus on COVID-19 effects

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Additionally, pro-inflammatory cytokines, such as Fas and TNF-, released by CD4 + helper T cells and macrophages, amplify inflammation and apoptosis, further contributing to hepatic injury [53]