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The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats

We have shown previously that sirtuins SIRT1 and SIRT3 have anti-fibrotic function, and their decreased tissue expression observed in skin biopsies from SSc patients, might directly contribute to the persistence of fibrosis 28,29

It is injected subcutaneously (under the skin) of the upper thigh, stomach (abdomen), or upper arm once weekly

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