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Contraindications Do not use Semax if you: Are pregnant or breastfeeding (insufficient safety data) Have uncontrolled hypertension Have severe psychiatric conditions (particularly acute psychosis) Have known allergy to Semax or its components Use with caution if you: Have diabetes (Semax may increase blood glucosemonitor levels) Have anxiety disorders (may worsen anxiety in some individuals) Are taking psychiatric medications (potential interactions) Have a history of seizures Drug interactions Semax affects multiple neurotransmitter systems, creating potential for interactions: SSRIs/SNRIs: Combined serotonergic effectsmonitor for symptoms of serotonin syndrome MAOIs: Avoid combination due to catecholamine and serotonin interactions Antipsychotics: May reduce Semax effectiveness or vice versa Other nasal medications with vasoconstrictive effects: Avoid concurrent use For a broader overview of peptide safety, see our peptide safety and risks guide

Key Scientific Features High-purity Hexarelin Acetate (98% by HPLC/MS, acetate salt form) Verified hexapeptide sequence with D-2-Me-Trp modification: His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH Lyophilized formulation for long-term stability Full Certificate of Analysis (COA) with HPLC, MS, and amino acid analysis Manufactured in GMP-aligned, ISO-compliant facilities Studied in the context of GHS-R1a and CD36 receptor signaling research Research-Referenced Attributes (Based on scientific literature