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Oxidative stress induced by hepatitis viruses, such as HBV and HCV, contributes to the development of hepatocellular carcinoma 82

e , ROS levels (DCF staining) in BT474 cells treated with ML210 for 1 h

10.1016/j.biopha.2024.117283 162 YangY.SangwungP.KondoR.JungY.McconnellM

2.3 Semi-mechanistic population pharmacokinetic modeling The popPK model was established using a nonlinear mixed-effects modeling approach implemented in NONMEM (version 7.4