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Key Takeaways Nicotine leaves the body quickly, but its metabolite lasts much longer: Nicotine itself is usually eliminated within 13 days, but cotinine (the primary metabolite tested for) can remain detectable for up to 10 days in blood and up to 3 weeks or longer in urine for heavy users

aged 18-35 years) were recruited from public spaces (e.g., libraries, parks, sporting events, shopping malls) to complete the 20-min experiment and received a $10 gift card for their time and effort

[168] Soon after smoking was introduced outside of the Americas it began appearing in painting in Europe and Asia

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